Jim,
Thanks for your help. I reviewed the standard QDX installation document, and I couldn’t find any mention of having to have our production processes/threads stopped to do an install (other than when the server has to be rebooted at the end of the install).
The documentation I received from our HIS vendor contradicts this; their documentation mentions having our engine stopped when doing both the install of 5.4.1 and the migration (hcirootcopy, hcixltconvert, etc.).
Thanks again.