One issue we had to resolve in the engine was to concat the nursing station with the room. You will need to do this if you have the same bed number defined in more than one nursing station. Examples are swing beds or a bed/cart that is defined in multipe units (ER cart 1 NU bed 1). So instead of sending a location of W2^225^1 we send it as ^W2225^1.
Extracting the Series pharmacy drug master was a fun little task as well. Then pharmacy had to spend weeks modifing the data for import into HMM.
If I remember anything else, I will post again.
We run Series 2000, PYXIS and HMM.
