Jared,
I can’t say that we have had it happen in a production environment, however in our test environment I have had something similar happen. I attribute it to the number of processes running on this box. Now I am sure this will open a can of worms on this thread, many have opinions on the number of threads and processes a site can have. Unless you are running Windows a limitation does not exsist according to support. However your hardware can only handle so many processes and threads before so weird things start to happen.
We are cutting back on the number of threads and processes in our test site until we can get that box upgraded.
Just my 2 cents,
Brian