We are doing something similar, sending HL7 messages from our cloverleaf engine lab results to the Physician offices the sysytem they purchased. We are doing this via secure VPN tunnel.
We are only the sending system and we don’t get anything back (except ofcourse the acks back). We are the initiaters. So far we have not got inot any problem.
We have done such a thing with one other system.
I am not exactly the right person to give details as what goes with the VPN tunnel and what may be..
but just to tell you, we are not seeing any issues..