Utilizing SQLite table within an Xlate

I’ve got a lab system that will be sending a new order description file nightly, for which I will pick up, drop the previous SQLite table that I’m building from it, and then recreate that table from the new nightly file.

My quesions is:  Will my process need to be bounced after I recreate the SQLite table so that my Xlate used between threads in that process will always pick up the correct values from the SQLite table, i.e. is there a cache to have to worry about?

Thanks, in advance.

Joe